1. One of the two main routes of blood coagulation cascade initiated by tissue damage and involving tissue factor (TF) and Factor VII
The extrinsic pathway is triggered when tissue factor is exposed following vessel injury.
A via extrínseca é acionada quando o fator tecidual é exposto após lesão vascular.
2. A rapid coagulation route that results in the production of thrombin and fibrin clot formation
The extrinsic pathway generates thrombin more quickly than the intrinsic pathway.
A via extrínseca gera trombina mais rapidamente do que a via intrínseca.