1. The outermost or farthest parts of something, especially the limbs of the body (hands, feet, arms, legs)
The patient complained of numbness in his extremities.
O paciente reclamou de dormência em suas extremidades.
2. The utmost degree or limit of something; an extreme condition or situation
The family was driven to extremities by poverty.
A família foi levada aos extremos pela pobreza.
3. Points or places that are farthest away; the ends or edges
The extremities of the island were largely unexplored.
As extremidades da ilha eram em grande parte inexploradas.