extracellular space

[/ˌɛkstrəˈsɛljələr speɪs/]
nounpl: extracellular spaces
espaço extracelular
1. The region outside of cells in tissues, containing interstitial fluid, proteins, and other molecules that facilitate cell communication and nutrient exchange
Ions move through the extracellular space to maintain cellular osmotic balance.
Os íons se movem através do espaço extracelular para manter o equilíbrio osmótico celular.
2. In anatomy and physiology, the compartment of the body that is not contained within cells, typically comprising about 15% of body weight
The extracellular space contains cerebrospinal fluid in the brain and interstitial fluid in tissues.
O espaço extracelular contém fluido cerebrospinal no cérebro e fluido intersticial nos tecidos.
3. The microenvironment surrounding cells that plays a crucial role in cell-to-cell signaling and tissue organization
Growth factors diffuse through the extracellular space to reach target cells.
Os fatores de crescimento se difundem através do espaço extracelular para alcançar as células-alvo.
This is primarily a scientific and medical term used uniformly across both Brazilian Portuguese and European Portuguese-speaking regions. It is essential terminology in biomedical research, medicine, and cellular biology education. The term reflects the globalized nature of scientific nomenclature, with minimal regional variation.
Synonyms / Sinônimos
interstitial spaceextracellular compartmentinterstitial fluid spaceextracellular environment
Antonyms / Antônimos
intracellular spacecytoplasmnucleus

Regional Variations

General Brazilian
espaço extracelular
Standard medical and scientific terminology used in universities and hospitals
São Paulo
espaço extracelular
Commonly used in medical research institutions and pharmaceutical companies
Rio de Janeiro
espaço extracelular
Used in medical schools and research centers with same standard terminology
Portugal
espaço extracelular
Identical terminology used in Portuguese medical and biological sciences

Related Words

interstitial fluidextracellular matrixcell membraneosmosisdiffusionion transporttissue fluidextracellular proteins

Related Idioms & Phrases

extracellular space and intracellular space together form the total body water
maintaining proper osmotic balance across the extracellular-intracellular boundary
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