1. A state of significant physical or emotional unease, pain, or dissatisfaction that is severe or pronounced
The patient complained of intense discomfort in his lower back.
O paciente reclamou de desconforto intenso nas costas.
2. A strong feeling of being uneasy, embarrassed, or troubled in a particular situation
There was intense discomfort in the room after the awkward silence.
Havia desconforto intenso na sala após o silêncio constrangedor.