1. to reduce or use up the supply or quantity of something
Overfishing depletes fish stocks in the ocean.
A pesca excessiva esgota os estoques de peixe no oceano.
2. to exhaust the strength, energy, or resources of someone or something
The long journey depletes her energy.
A longa jornada esgota sua energia.
3. to reduce the amount of a substance in the body or environment
Excessive sun exposure depletes vitamin D production in some cases.
A exposição excessiva ao sol esgota a produção de vitamina D em alguns casos.