conservative replication
[kən-ˈsər-və-tiv ˌre-plə-ˈkā-shən]
noun
replicação conservadora
1. A hypothetical model of DNA replication in which the original DNA double helix remains intact and an entirely new double-stranded copy is synthesized, resulting in one original and one completely new DNA molecule
Conservative replication would produce one original DNA molecule and one entirely new DNA molecule after one round of replication.
A replicação conservadora produziria uma molécula de DNA original e uma molécula de DNA completamente nova após uma rodada de replicação.
2. A theoretical mechanism of DNA replication that was disproven by the Meselson-Stahl experiment in 1958, which demonstrated that semi-conservative replication is the actual mechanism
The Meselson-Stahl experiment ruled out conservative replication as the actual mechanism of DNA replication.
O experimento de Meselson-Stahl descartou a replicação conservadora como o mecanismo real da replicação de DNA.
This is a technical term used exclusively in molecular biology and genetics education. It has historical significance in the development of molecular biology, as its disproval by the Meselson-Stahl experiment in 1958 was a pivotal moment in understanding how DNA actually replicates. The term is used identically in both English-speaking and Portuguese-speaking scientific communities.
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