1. The most important or fundamental problem, topic, or matter at the core of a discussion, debate, or situation
The central issue in the debate was whether to raise taxes or cut spending.
A questão central do debate era se deveria aumentar impostos ou cortar gastos.
2. The primary concern or main point that requires resolution or attention
Environmental protection remains the central issue for this political campaign.
A proteção ambiental continua sendo a questão central desta campanha política.