Factor VII-dependent pathway

[ˈfæktər ˈsɛvən dɪˈpɛndənt ˈpæðweɪ]

nounpl: Factor VII-dependent pathways

via de coagulação dependente do Fator VII

1. A blood coagulation cascade pathway initiated by tissue factor (TF) and Factor VII that leads to the activation of Factor X, marking the beginning of the common pathway in blood clotting

The Factor VII-dependent pathway is crucial for initiating the extrinsic coagulation cascade when tissue damage occurs.

A via dependente do Fator VII é crucial para iniciar a cascata de coagulação extrínseca quando ocorre dano tecidual.

2. In medical contexts, the initial stage of blood clotting that occurs when Factor VII binds to tissue factor at the site of vascular injury

Deficiency in Factor VII can impair the Factor VII-dependent pathway, leading to bleeding disorders.

A deficiência do Fator VII pode prejudicar a via dependente do Fator VII, levando a distúrbios hemorrágicos.

Synonyms

extrinsic coagulation pathway tissue factor pathway TF/Factor VII pathway

Antonyms

intrinsic coagulation pathway contact activation pathway

Regional Variations

General Brazilian

via de coagulação dependente do Fator VII

standard medical terminology used throughout Brazil

Portugal

via de coagulação dependente do Factor VII

uses 'Factor' spelling following European Portuguese convention

General Medical Portuguese

via extrínseca da cascata de coagulação

alternative descriptive term used in medical literature

Related Idioms & Phrases

initiate the coagulation cascade

trigger the extrinsic pathway

Factor VII-dependent activation of Factor X

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