DNA polymorphisms
[/ˌdiː ɛn ˈeɪ ˌpɑːlɪˈmɔːrfɪzəmz/]
nounpl: DNA polymorphisms
polimorfismos de DNA
1. Variations in DNA sequences that occur in different individuals or populations, where two or more different DNA sequences exist at the same location (locus) on a chromosome
DNA polymorphisms are used as genetic markers in forensic investigations and paternity testing.
Os polimorfismos de DNA são utilizados como marcadores genéticos em investigações forenses e testes de paternidade.
2. Natural genetic differences between individuals that can be detected through DNA analysis, including single nucleotide polymorphisms (SNPs), insertions, deletions, and other variations
Researchers study DNA polymorphisms to understand genetic diversity and disease susceptibility.
Os pesquisadores estudam polimorfismos de DNA para compreender a diversidade genética e a suscetibilidade a doenças.
3. Inherited variations in DNA sequences that are present in at least 1% of the population
DNA polymorphisms can explain why individuals respond differently to medications.
Os polimorfismos de DNA podem explicar por que os indivíduos respondem diferentemente aos medicamentos.
DNA polymorphisms is a specialized scientific and medical term used in genetics research, forensic science, and personalized medicine in both Brazil and the USA. It is fundamental to modern fields such as pharmacogenomics, population genetics, and forensic DNA analysis. In Brazil, this terminology is standard in universities, research institutions like Universidade de São Paulo (USP) and Universidade Federal do Rio de Janeiro (UFRJ), and in clinical and forensic laboratories. The study of DNA polymorphisms has significant implications for understanding disease susceptibility, drug response variation, and human evolutionary history across populations.
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