DNA fragmentation

[/ˌdiːɛnˈeɪ ˈfræɡmənˈteɪʃən/]
nounpl: DNA fragmentations
fragmentação de DNA
1. The breaking down or breakage of DNA molecules into smaller pieces or fragments, either naturally during cell death or artificially in laboratory conditions
DNA fragmentation is a key indicator of apoptosis in cancer research.
A fragmentação de DNA é um indicador-chave de apoptose em pesquisa de câncer.
2. A process occurring during programmed cell death where nucleases cleave DNA at internucleosomal sites
Researchers observed DNA fragmentation in the sperm samples, which affected fertility.
Os pesquisadores observaram fragmentação de DNA nas amostras de esperma, o que afetou a fertilidade.
This is a technical scientific term primarily used in medical, biological, and forensic research contexts in both Brazil and the USA. In Brazilian scientific publications, 'fragmentação de DNA' is the standard terminology, while in Portugal 'fragmentação de ADN' is preferred due to Portuguese nomenclature conventions for nucleic acids.
Synonyms / Sinônimos
DNA breakdownDNA degradationnucleosomal fragmentationinternucleosomal cleavage
Antonyms / Antônimos
DNA integrityDNA stability

Regional Variations

General Brazilian
fragmentação de DNA
Standard term used in scientific and medical contexts across Brazil
Portugal
fragmentação de ADN
Portuguese uses ADN instead of DNA, though DNA is also understood in scientific contexts

Related Words

apoptosisnecrosiscell deathnucleasechromosomal aberrationgenotoxicity

Related Idioms & Phrases

DNA fragmentation assay
DNA fragmentation index
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